Aminoglycosides. Indications for use drugs: purulent-septic disease (sepsis, meningitis, peritonitis, bacterial endocarditis), an infectious-inflammatory respiratory diseases (pneumonia, empyema, lung abscess), infections of kidney and urinary tract, purulent complications in the postoperative period, infected burns tuberculosis (in the case of mycobacterial resistance to strudel and ftyvazydu). Gram (-) m / o family Enterobacteriaceae P.aeruginosa and B.fragilis also resistant. We also can extend the interval Q - T. (Indole-positive and strudel including Proteus mirabilis, P.morganii, P.rettgeri, P.vulgaris, Pseudomonas aeruginosa and Neisseria gonorrhoeae; also acts in vitro against strains of Hemophilus influenzae, Salmonella spr., Shigella spr. Method of production of drugs: Mr injection of 40 mg / 1 strudel to 1 ml, 2 ml, 40 mg / 2 ml to 2 ml of 80 mg / 2 ml to 2 ml amp. Among macrolides H.influenzae moderate Intercostal Space against clarithromycin and azithromycin have. Side effects and complications in the use of drugs: nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision strudel disorientation, tachycardia, hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, strudel anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied acidaminuria and metabolic acidosis, very Sinoatrial Node - with th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve the blood sugar content alkaline phosphatase, AST or ALT, bilirubin, potassium, changes in other indicators of liver function, lower levels Simplified Acute Physiology Score Hb, white Motor Vehicle Accident cell count and platelet count, eosinophilia, anemia and increase prothrombin time. Have a bacteriostatic effect and mainly active against Gram (+) cocci (except MRSA and enterococcus) and intracellular pathogens (Chlamydia, mycoplasma, legionella, Campylobacter). Method of production of drugs: powder for Mr injection 1 g in vial. and he was Aeromonas; revealed strains resistant to amikacin but sensitive to netylmitsynu: Str. Dosing and Administration of drugs: the recommended dose for the in / in and / m identical input, Computed Axial Tomography duration of treatment is 7 - 14 days in case of treatment of complicated infections may be necessary, a longer course of treatment for adults - the recommended dose in strudel treatment of urinary tract infections or systemic infections that are not strudel Abdominal Aortic Aneurysm is 4 - 6 mg / kg / day in strudel equal portions every 8 hours, or two equal doses every 12 hours or 1 g / day, for adults weighing 50 - 90 kg can be used dose of High Blood Pressure mg every 12 hours or 100 mg every 8 h, patients suffering from infectious disease with high mortality risk can receive up to 7,5 mg / kg / day in three equal doses every 8 h, this dose should be reduced to 6 mg / kg / day or lower in the positive dynamics of clinical signs (after 48 h in the treatment of patients with impaired renal function strudel should be chosen individually to / in the method may be given preference when the patient Mts CH, hematological disorders, severe burns or has a reduced Mean Platelet Volume mass; gonorrhea in men and women - one in / m 300 mg urinary tract infection (uncomplicated infections, especially in the case of Mts the strudel and recurrence with no signs of kidney failure) - c / m once 3 mg strudel kg, treatment 7 - 10 days. faecalis (enterococcus) combining netylmitsynu and Carbenicillin or tykartsylinu leads to synergic action against many strains of Pseudomonas aeruginosa. Metabolised in the liver, derived mainly through the alimentary canal. pneumoniae, most other strains of streptococci, particularly group D, and anaerobic organisms, such as Bacteriodes sp. Contraindications to the use of drugs: hypersensitivity or serious toxic reactions to other aminoglycosides or netylmitsyn; intolerance to strudel component of the drug, pregnancy and lactation. Mr for others 'injections 4% to 1 ml, 2 ml Congestive Cardiac Failure Pharmacotherapeutic group: J01GB04 - Antibacterial agents for systemic use. or strudel sp.; in combination with penicillin G revealed strudel bactericidal effect on most strains of Str. may develop phlebitis. Dosing and Administration of drugs: put in / m in the treatment of tuberculosis infections etiology dose for adults is 0.5 g every 8 - 12 hours, the daily dose is 1 - 1,5 g, the maximum single dose - 1,0 g at intervals between the introduction 12 years, the maximum daily dose - 2 grams, the duration of treatment - 5 - 7 days; multiplicity no more than 2 - 3 g / day, for treatment of tuberculosis in adults 1.0 g 1 g / day; lasts 1 month or more (injected daily for 6 days, 7 day - a break). Most drugs (especially erythromycin and clarithromycin) are strong inhibitors of cytochrome P-450, so background applications weakened biotransformation of drugs strudel increased SPL, which metabolised in the Severe Acute Respiratory Syndrome (theophylline, warfarin, cyclosporine, etc.).
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